Objectives

• Promote the investigation of the role of glycans in the modulation of autophagy, endocytosis and lysosomal functions in cancer.
• Promote the investigation of the role of glycans in the modulation of autophagy, endocytosis and lysosomal functions in lysosomal disorders.
• Promote the investigation of the role of glycans in the modulation of autophagy, endocytosis and lysosomal functions in neurodegenerative diseases.

Tasks

• Employ advanced techniques to track the glycosylation pattern of glycoconjugates associated to autophagy, endocytosis and lysosomal functions.
• Promote the identification of relevant model systems to investigate the glycan dependent modulation of autophagy, endocytosis and lysosomal functions.
• Boost the development of modulators of autophagy, endocytosis and lysosomal functions (nanometric, small molecules and glycoconjugates).